Scriptures Against Depression


Grief-and-Depression350-webDepression is real, and if you are fighting it you are not alone. Depression seems to have been the bane of many of life’s great leaders. In the Bible, Moses, Elijah, David, and Job all had to deal with it. In the secular world, Sir Winston Churchill called depression his ‘black dog’, and Ernest Hemingway referred to it as ‘the artist’s reward’.

President Abraham Lincoln battled depression and suicide all his adult life. There were times when for his own safety Lincoln would not allow himself to carry a knife, for fear that he would hurt himself, or worse. Read about Lincoln turning to the Bible to relieve his depression. Let the Scriptures help you just like they have helped so many of us. And sometimes depression can be a purely spiritual thing, read this – Depression Is a Spirit – It Must Be Fought with the Word of God.

Depression is the physical and emotional result of hopelessness – the ‘feeling‘ of hopelessness. We live in a world devoid of hope, and depression is the emotional product of that reality. The only thing that will actually change one’s life sufficiently as to destroy the cause, mechanics, and effects of depression is God’s hope and His word of hope. The answer is to get God’s hope back inside of you.

Hope will let you again see the ‘future positive possibility’ of your life. Without seeing it you will have no motivation or strength. The good Word of God, and the good word of others to you, can change the outlook and condition or your heart. Fight for God’s outlook with all you have. Fight it with the Word of God. (Also, confess the scriptures on Hopelessness.) Anyone who is among the living has hope.

God’s hope encourages, motivates, and keeps you on the road to faith, peace, and victory. And if you suffer from deep ongoing depression, seek out and get help. And please read this – Helping Others Is God’s Prescription for Depression. Send me a comment, we love you  and we want to help you. You are important and you have value. You are not alone. With God’s help, you will climb out of this hole.

Anxiety in a man’s heart weighs it down (depression), but a good word cheers it up. Proverbs 12:25 Holman Christian Standard Bible

These scriptures on depression will give you hope and will build your faith. Confess and meditate on them to win the fight against depression. The key is not losing Hope. Allow the hope of God to seep back into you. Remember, there is a real Person (God) behind each and every one of these promises. He promised them to you for a reason – to help you.

Deuteronomy 31:8 – The Lord himself goes before you and will be with you; he will never leave you nor forsake you. Do not be afraid; do not be discouraged.

Deuteronomy 33:27 – The eternal God is your refuge, and underneath are the everlasting arms.

2 Samuel 22:17-22 – He sent from above, he took me; he drew me out of many waters; (18) He delivered me from my strong enemy, and from them that hated me: for they were too strong for me. (19) They prevented me in the day of my calamity: but the Lord was my stay. (20) He brought me forth also into a large place: he delivered me, because he delighted in me. (21) The Lord rewarded me according to my righteousness: according to the cleanness of my hands hath he recompensed me. (22) For I have kept the ways of the Lord, and have not wickedly departed from my God.

2 Samuel 22:29 – You are my lamp O Lord; the Lord turns my darkness into light.

Ecclesiastes 9:4 – Anyone who is among the living has hope.

Psalms 9:9 – The Lord is a refuge for the oppressed, a stronghold in times of trouble.

Psalm 27:14 –  Wait on the LORD: be of good courage, and He shall strengthen thine heart: wait, I say, on the LORD.

Psalm 31:22,24 – You heard my cry for mercy when I called to you for help… Be strong and take heart, all you who hope in the Lord.

Psalm 34:18, 19 – The LORD is close to the brokenhearted and saves those who are crushed in spirit. (19) A righteous man may have many troubles, but the Lord delivers him from them all.

Psalm 37:23-24 – If the Lord delights in a man’s way, he makes his steps firm; though he stumbles, he will not fall, for the Lord upholds him with his hand.

Psalm 43:5 – Why are you downcast, O my soul? Why so disturbed within me? Put your hope in God.

Psalm 55:22 – Cast your cares on the Lord and he will sustain you; he will never let the righteous fall.

Psalm 62:5 – Find rest, O my soul, in God alone; my hope comes from him.

Psalm 126:5 – Those who sow in tears will reap with songs of joy.

Psalm 143:7-8 – Answer me quickly, O Lord; my spirit fails. Do not hide your face from me or I will be like those who go down to the pit. Let the morning bring me word of your unfailing love, for I have put my trust in you. Show me the way I should go, for to you I’ll lift up my soul.

Psalm 147:3 – He heals the brokenhearted and binds up their wounds.

Psalm 145:14 – The LORD upholds all those who fall and lifts up all who are bowed down.

Proverbs 12:25 – Anxiety in a man’s heart weighs it down (depression), but a good word cheers it up.

Isaiah 26:3-4, Thou wilt keep him in perfect peace, whose mind is stayed on Thee: because he trusts in Thee. Trust ye in the LORD for ever: for in the LORD JEHOVAH is everlasting strength. (Perfect means complete. If I keep my part of the promise by staying steadfastly focused on the Lord Jesus Christ, He will keep His promise to give me His perfect peace. See also Philippians 4:6-7 below)

Isaiah 35:10 – And the ransomed of the Lord will return. They will enter Zion with singing; everlasting joy will crown their heads. Gladness and joy will overtake them, and sorrow and sighing will flee away

Isaiah 40:31, But they that wait upon the LORD shall renew their strength; they shall mount up with wings as eagles; they shall run, and not be weary; and they shall walk, and not faint.

Isaiah 53:4 – Surely he took up our sicknesses and carried our sorrows.

Mark 9:23 – Everything is possible for him who believes.

Romans 4:18-22  – Who against hope believed in hope, that he might become the father of many nations, according to that which was spoken, so shall they seed be. (19) And being not weak in faith, he considered not his own body now dead, when he was about an hundred years old, neither yet the deadness of Sarah’s womb: (20) He staggered not at the promise of God through unbelief; but was strong in faith, giving glory to God. (21) And being fully persuaded that, what he had promised, he was able to perform. (22) And therefore it was imputed to him for righteousness.

Romans 15:13 – May the God of hope fill you with all joy and peace as you trust in him, so that you may overflow with hope by the power of the Holy Spirit.

II Corinthians 7:6-7  – Nevertheless God, that comforts, those that are depressed, comforted us by the coming of Titus; (7) And not by his coming only, but by the consolation wherewith he was comforted in you, when he told us your earnest desire, your mourning, your fervent mind toward me; so that I rejoiced the more.

Philippians 4:6-7 – Be anxious for nothing, but in everything by prayer and supplication with thanksgiving let your requests be made known to God. And the peace of God, which surpasses all comprehension, will guard your hearts and your minds in Christ Jesus.

James 4:8 – Come near to God and he will come near to you. Wash your hands, you sinners, and purify your hearts, you double-minded.

James 4:10 – Humble yourselves before the Lord, and he will lift you up.

2 Peter 2:9 – The Lord knows how to rescue godly men from trials.

1 Peter 4:12 – Dear Friends, do not be surprised at the painful trial you are suffering, as though something strange were happening to you.

1 Peter 4:13 – But rejoice that you participate in the sufferings of Christ, so that you may be overjoyed when his glory is revealed

1 Peter 5:7 – Cast all your anxiety on him because he cares for you.

Read how Lincoln Turned to the Bible to Manage His Depression and other articles: Scriptures Against HopelessnessScriptures Against WorryNew Testament Scriptures on Faith & BelievingDo God’s Promises Cover What You Want?

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Comments 490

  1. lupe valdez

    My prayers I been struggling also with depression for years I continue to fight but it’s never easy. I pray and cry alot there’s a part of me feels like why is this happening but I continue my fight because I pray to jesus and god and it’s the best thing to do. I pray in Jesus name that we all be healed in Jesus name. Any one can call me if they ever want to talk things out number is 505 449 8457 lupe valdez

  2. Linda Cox

    Do not give up. That is what the enemy of our souls wants us to do . His job is to kill,steal, and destroy. Jesus said I have come to give you life ,abundant life. He wants you to be filled with His peace. Accept His love and forgiveness and be filled l ed with His Spirit I pray in Jesus name amen.
    He will deliver you from all evil forces you just have to call out to Him and plead the blood of Jesus over yourself and the enemy will have to leave.
    Speaking God’s Word is your protection tion. Ephesus 6:10-17

  3. Katie Haney


    My name is Katie. My boyfriend has been dealing with anxiety and depression for over 7 months now. It has been very hard on us all. He seems to be sinking down farther and farther and it seems to be harder and harder for him to keep fighting . He struggles with having faith in the Lord to help him through this. He is at a job that doesn’t seem to make him happy anymore. He makes good money and has a lot of perks with the job and is a supervisor so its very hard to give this job up. He has been looking for something else but hasn’t seem to found anything. We both have been praying for the Lord to help him find a job that he likes and for the Lord to show him some answers. He struggles with keeping faith in anyone or anything. He gets very discouraged and very depressed. He is at the point he wishes something would happen to him where he doesn’t have to keep fighting. I have always been a believer and always had faith in the Lord so its hard for me to understand where he is coming from. I try my best to show him gods grace and pray for the Lord to show him answers and bring his peace and comfort. It seems like the more I pray for him the worse he gets. I can feel satan surround him and feel him give in to satans words. He gets to the point where it would be easier to just give up and not fight . He feels very tired of living this life and just wants to find happiness again. He has trouble with having faith in the lord and I feel like my words don’t mean anything to him anymore. He started going to church and talking to a counselor and reading his bible but still struggles to find the answers he is looking for. He is on medications for anxiety and depression but don’t seem to be working. I feel at a loss right now. I don’t know how to help him if he pushes away God and everyone who loves and cares for him. I guess I’m looking for help and answers through this as well. We have been together for 5 years and raise a 7 year old daughter together. Its hard for me not to just want to give up on him and end it . I just wish he could feel that hope and faith that I have.

    1. Kay

      Dear Katie, how hard it is to watch someone you love struggle, and even worse give up, and there’s little you can do to help, so it is very important that you don’t let your faith slacken because that is all your boyfriend has right now. Look up the movie “War Room” and if at all possible you both should see it, it is about someone who has given up and their struggle to fight Satan and regain their faith. Right now you have to keep supporting him. If your church has a prayer group, join it. Maybe you can help him search for a new job or even just a new activity to engage him. Get him involved in something with the child you are raising. Most of all, do not give up. I will pray that God blesses you both.

  4. Shakira

    i am so glad I found this site. I have been off and on with depression for a few years and just a couple of days ago, I sank back into it really bad and after reading these scriptures, my heart feels lighter and I feel a little better so far. please keep me and others who are currently going through things in life in your prayers.

  5. Padilla

    I am thankful for finding this site. I have been depressed since as early as I can remember and have struggled my entire life with manic depression and suicidal temptations. I pray to God for forgiveness for being weak and tempted to take the easy way out. I pray for strength and I try to see the good in everyday, but I need help. Therapy and medication have not helped. Dear God, please save me. Please pray for me. I am 26 years old and cannot not do not want to go on much longer living like this. My depression is consuming me. I can’t breathe. All my love to those in pain and those who try to help.

    1. Kay

      Padilla – please read Shakira’s message and feel the hope she now enjoys. You are never alone. Aside from being in so many people’s prayers from this site, God really is always with you. I don’t know why we must sink so low, I have been there, too, in fact part of my constant prayer is that He be especially with those who feel alone and that they feel his gentle hand upon their shoulder. Please speak to someone you are close to or your Pastor and if you don’t have one, find a church, somewhere God is waiting for you. Please be blessed and do not, ever, give up!

  6. Cathy

    I came across site looking for scriptures to help me through my depression . I have been diagnosed as having severe depression. I lost both my parents within 4 months of each other. My boyfriend who was in my life for a few years asked to move in with me. I would not let him move in with me as I choose to live the Godly life and not live in sin. He in turned moved in with another woman and married her and said it was my fault and my choice. That brought me over the top. My life feels so lonely and empty to the point I feel life is not worth living anymore. I would never harm myself though but sometimes I pray and wish that God would just let me sleep away. I feel like a failure and I don’t know if I’ll ever get back to being happy. I’m trying and praying so hard to bounce back but so far I’m not able. I need something to give me hope again because I feel so broken. Please pray for my strength as it is failing me.

    1. Post

      Cathy – You did the right thing with your boyfriend. It is him with the failure problem not you. If you could see correctly you would realize how well off you are now because of it. The Devil is using your loss and hurts to paint a black picture of everything.

      Hopelessness does not mean that there is no hope for you. As a Christian you always have hope in Christ. What it means is that you cannot see the hope that is there all around you. It is a blindness to hope, and you know where that comes from – a spirit sent to harass you. Read this – Depression Is a Spirit – It Must Be Fought with the Word of God. And read this article – You Cannot ‘Out Think’ the Devil But You Can ‘Out Speak’ Him.

      God’s word can help you but you have to work it and do your best to not be guided by your feelings. The Devil has somehow gotten control of your sight and your feelings, so you will have to ignore them for a while. Speak the word intensely no matter what you see or how terrible you feel. We love you. You are not alone. You will make it. The light is around you. Speaking His word will help open your eyes to it. Rex

    1. Post

      Leslie – I don’t doubt your sincerity or perseverance, and I felt that you really were praying all day everyday. My point is – something is not working. Do something different and find out what that thing is. Change the way you pray, what you pray, or take the scriptures and walk the floor and speak them out of your mouth till they are totally part of you. They are not now, otherwise you would not be thinking about dying and so depressed. Something is not connecting, so you don’t necessarily need to double-down on what you already are doing. Read the most recent post on our site.

      As a Christian, we are going to go through stuff, sometimes deep stuff, but there is a victory for us in faith, and I do not mean dying and going to Heaven. There seems to be an issue that is holding you back. Find out what it is and deal with it. Faith is of the heart but the realm of the battle seems to be centered in our minds. Many times we cannot fully control our minds but we can control what we say with our mouth. That is the essence of the article I mentioned above. Joyce Meyer has a lot of good things to say on this.

      There is a path to victory for you. The victory will not be overnight but the peace and joy can quickly return so that you can make it all the way to the end. There is a path, find it. We love you. God loves you. Rex

    1. Post

      Leslie – We do love you. You will make it. Seek God knowing that there is an answer, and that you just have to find it – in Him. That is a much different approach than hopelessly crying out for a miracle. There can be and will be a miracle, but you must seek Him with an expectant heart, that is a trusting heart.

      The more of the Bible you can get inside of you the easier it will be. Let God speak to you while you are reading and praying. Rex

    2. Kay

      Leslie – pray loudly and boldly for God to ease your burdens. Even though He knows what is happening with us, He wants us to verbalize it to Him to express our faith and trust. You are in my prayers.

  7. Felicia

    I have been depressed for sometime. After losing my oldest sister in 2014, l have gradually started bck living. But somethings have changed l just do not desire somethings l used too. I am a loner l have two daughters that depend on me, l have been out of my place since May 2015. I am asking through prayers that financially l will be blessed with a place for my family. The bible tells us to die to the flesh everyday, and l honestly know that it is the holy spirit that has changed my mind about fornication. I feel so filty when engaging in unGodly acts. I just want to uplifted and assured l am doing the right thing and not feel like l am not. My prayer tonight is for Mental Healing, strength to regain what the enemy has stolen from me! And continue closing doors on ppl that are no longer needed in my life. I Am Depressed almost everyday, l have crying spells, but will never attempt anything as foolish as sucide. Please keep me and family in prayers.

    1. Dave

      Lord Jesus..Give this sweet woman peace in her life..Joy to her heart.Fill her with Hope..let her recognize the doors she should walk through..let her rebuke the tempations satan throws at be strong and keep her safe in your loving arms..In Jesus Name I pray this..AMEN

  8. Kay

    Bash, I am so sorry you feel that way. Please read the comments below and you will see that you are not really alone, so many people feel just as you do. My bible class is studying how to pray and the most important thing is that God wants us to pray boldly and fervently, whether we are asking for something for ourselves or for others. We should build prayer circles around our wants and as we walk the circle we keep repeating our request, and we must be specific, not have a general “peace on earth” type prayer. We can write down what we ask for and draw a circle around it and keep praying every day at about the same time, making our prayers louder and more passionate each time, and keep at it until our prayers are answered. Sometimes the biggest problem is to pinpoint what is our Jericho (they walked around the city for seven days before the walls fell down), but we should try. I will pray that God eases you and helps you see that life will be better for you because God does love you!

  9. bash

    Hi, I just stumble on this site hoping a word might strike me to feel hope again. I believe I have depression, started having test online and results say I have severe or major depression. My life is so lonely, so empty, so not worth living. I do not think of committing suicide though, I just sometimes I would pray that God would take this life away, never to be awoken from sleep. I cry for almost everyday, I feel helpless, hopeless, very sad.. it just so hard to be happy, I feel like my life is such a failure.. I’m 33yrs old, female, and I feel like a nobody. this world just isn’t for me. Sometimes I would ask God why Jesus hasn’t return yet, when will the world end? because I want it to end.. enlighten me and please pray for me.

    1. natalie johnson

      you are not along.. I am feeling the same way too.. I will keep you in my prayers… Depression is a trick from the enemy.. becuz most of the times u don’t even realize u are depressed… I been have issues aches pains n headaches and have gone to the dr n don’t see any reason for my issues. and now I realize all my physcial pains come from me being clinical depressed..

  10. Theresa

    I have a 12 yr. old grandson who is sad and I believe depressed. His name is Daniel, he is also a believer! Please pray for him, he’s gone through many, many changes in his life.

    Thank you,

  11. leslie

    I have been suffering from depression and anxiety for years. I’m financially in a mess and I feel like things will never get better. I think about dying everyday and feel that my life is not worth living. I have been asking for God’s help, but nothing seems to change. Please pray for me

    1. Post

      Leslie – We will pray for you. You will walk out of this in Jesus Name. Scroll down the comments and find one of mine with a bunch of links. Use them to help you find out what is going on. Also, go to our homepage (hit the logo above on this page) and start with the latest article. Read those that jump out at you.

      Spend time with God. Do not beg but expect Him to answer. It is a spirit hindering you. Find out how to deal with it. We love you.

    2. John Decker

      Leslie, You are loved and Jesus has overcome for you. Give it to God. You are forgiven. Keep reading your bible.

  12. Kay

    Yvonne, I am sorry you are suffering such hurt. It is hard to think rationally when you’re feeling that pain. I’m glad God has helped you in the past and that you’ve had counseling but wonder if you have a regular church and pastor who might help you now? I have no magic words, but you are in my prayers.

  13. Rosa Smith

    I have been suffering with real bad depression & anxiety ever since my dad passed away on September 12th of last year. I hae been soooooooooooooooooooooo unsure of a lot of things lately. I have almost given up on God because of it. PLEASE KEEP ME IN YOUR PRAYERS. ALSO FEEL FREE TO EMAIL ME AS MANY SCRIPTURES AS YOU WANT

    1. Kay

      Rosa, I can understand your hurt from your dad’s passing. My father died a long time ago but many times I realize I will never stop thinking that he is the strongest most able man in the world who will always take care of me and protect me from everything. So when you add the sense of loss to someone who suffers from depression, you see that your feelings are quite normal. You asked for scriptures. Here is something I read that helped me, I hope it helps you, too (don’t know from where I copied it) . You will be in my prayers.

      Here are 21 reasons God may allow more than you can bear:
      So you will rely on him. 1 Peter 5:7 So you will call on him. Acts 17:26-27 So you have no choice but him. John 15:5 So he can tell us things we wouldn’t know otherwise. Jeremiah 33:3 So he can be gracious to you. Isaiah 30:18 So he can show his kindness and compassion. Lamentations 3:21-24 So he can restore your soul. Psalm 23:3 So he can demonstrate his strength. 2 Corinthians 12:9 So you will trust in Jesus — and the Father. John 14:1. So you can produce character and hope. Romans 5:3-5 So he can keep us from being self-reliant 2 Corinthians 12:7 So he can discipline his children. Hebrews 12:6-7 So God’s power is revealed. 2 Corinthians 4:7 So he can show our need for salvation. Psalm 119:67 So he can comfort us. 2 Corinthians 1:3-4 So we can learn to comfort others. 2 Corinthians 1:3-4 So he can reveal his unseen workings. Psalm 77:19 So he can demonstrate how all things work for an eventual good. Romans 8:28 So the Gospel might be proclaimed. Philippians 1:12-13 So he can draw prodigals home. Luke 15:17 So he can build character and hope. Romans 5:3-4 Don’t believe the lie. God will allow more on you than you can bear — alone. You and I need him for our every breath.If you feel overwhelmed today — defeated — like there is more on you than you can bear – turn to the burden bearer. “Then Jesus said, ‘Come to me, all of you who are weary and carry heavy burdens, and I will give you rest.’” (Matthew 11:28)

  14. Yvonne

    Please pray with me against depression, torment from rejection and loneliness. 4 years ago, my husband completely turned into the devil himself and left. I have prayed, had counseling, have others to pray, been on medication, and nothing seems to give me peace, this has completely changed me. I have been thru many trials in the past that God has helped me to overcome, but this situation seems to consume my very soul. I can’t seem to get past this thorn in my side.
    I pray for closure and to regain my peace, joy and be happy again.

  15. Yulanda

    Alicia, I do know the feeling of being lonely because I am lonely now. But I’m trusting and believing that my husband will come back home to me. If you need someone to talk to as a friend , you can hit me up and we can talk and be friends.

  16. David from Michigan

    Hello Alicia. Yes, I will pray to God for you, asking Him to grant you peace and comfort… the kind that only He can give, through His spirit. I am sorry that you are hurting. It must be a terrible thing to feel so lonesome.

    If you don’t mind saying, do you have anyone in your area who can give you counsel and advice about this? Someone you could talk to face to face? From my own experience, I know that a good counselor (whether that be a pastor, a priest, a rabbi, or a medical professional) can offer you different ways to look at how your life is going and suggest some things you could try that maybe you haven’t tried before. I think everyone at one time or another could get beneficial help from a good support system. We all need encouragement from time to time. At least I know I do, and it sounds like you do as well. Meanwhile, I will pray that God would bring someone along side you to be a friend.

    It looks like I am not the only one who will be thinking of you and going before the Lord for you. I suspect there will be more, as there are more than just a few people following these posts on the subject of depression. Warm regards to you.

  17. Alicia

    I need prayer. I am 35 years old and I have been lonely ever since I can remember. I don’t know what to do. It is so hard for me to make friends. I talk to people. I’m friendly but people still don’t like me for some reason. It’s been like this since childhood. I am so tired of going through life feeling lonely all the time and not even having a friend. I’ve been thinking about God. I believe in Him. I also believe I have a purpose. It just sometimes my loneliness just overwhelms me. I can’t take it anymore. Please, please someone pray for me.

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